We stayed in the center of the island, which I highly recommend, as you get views from both directions and a stunning look at the sunset every night. It also allowed us to do a fair amount of walking, up to the famous Blue Domed Church of Santorini on the northern end of the island (Oia). As well as down to where many bars and restaurants with rooftop patios, overlook the mountain goats and gondola that both easily disembark down the cliffside.